Associate Professor Vitali Sintchenko
University of Sydney
Associate Professor Vitali Sintchenko is a leading public health microbiologist and informatician who conducts research on biosurveillance of communicable diseases. He is a Fellow of the Royal College of Pathologists of Australasia and the Australian College of Health Informatics. As Director of the CIDM-Public Health (a translational research hub funded by NSW Health), he leads a public health and diagnostic microbiology team working toward improving laboratory and epidemiological investigations of communicable diseases. He is the Chair of the Commonwealth Public Health Laboratory Network.
A/Prof. Sintchenko is widely recognized for his contributions to the adaptive methods of molecular characterisation and genome analysis of pathogens with epidemic potential. He has published over 150 full-length peer-reviewed papers, 5 book chapters and 2 books with >700 citations. His research spans the domains of biosurveillance, molecular diagnostics and epidemiology of bacterial pathogens, as well as decision analysis and decision support. His team has proposed an innovative model of biosurveillance based on the integration of text mining and molecular epidemiology patterns and have advanced the theory and implementation of the “third-generation” surveillance systems, which are based on molecular genotyping. These systems enhance the timeliness and accuracy of biosurveillance signals.
His paper in Nature Microbiology Reviews laid the foundation for pathogen profiling utilising phenotype-based methods with genomics, proteomics, and sequence-based typing. This innovative approach significantly enhances our understanding of the transmission patterns and dynamics of epidemics. It also improves the efficiency of outbreak investigation and disease monitoring. The comparative genome sequencing analysis of Bordetella pertussis, Salmonella and Staphylococcus aureus isolates conducted with collaborators and funded by the NHMRC project grants, extended insights into microecology of bacterial communicable diseases, showed changes in epidemic strains that may be vaccine driven and identified emerging clones of public health concern. In 2008 Springer Life Sciences invited him to edit the first volume on Infectious Disease Informatics published in 2010. It reviewed informatics applications including genomics enabled surveillance (>10,000 copies sold in 3 years).
Qualifications: MBBS (Chernivtsi. 1983); PhD (Medical Informatics, UNSW, 2005); FRCPA (1999), FACHI (2006)
Address: Sydney Medical School – Westmead, Centre for Infectious Diseases and Microbiology, ICPMR Building, Westmead Hospital, Westmead NSW 2145
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